An announcement on his personal website said he had passed away at a hospital in La Jolla, California, on July 26.
Born in Oklahoma, Cale helped to create a new music style Tulsa Sound, which combined blues, rockabilly, and country. He became famous in 1970, when Eric Clapton covered his song "After Midnight".
In 1977 Clapton also popularised Cale's "Cocaine". The two worked together on an album which won a Grammy award in 2008. As a performer, his biggest hit was "Crazy Mama", which peaked at No 22 on the US Billboard Hot 100.
He pioneered the use of drum machines, and was famous for his personal laid-back singing style.
However Cale always described himself as a songwriter rather than a singer, and his songs gained him a permanent place in popular music history, as he wrote a string of songs that were made more famous by artists including Clapton, Santana, Lynyrd Skynyrd and Tom Petty.
