The president's remarks followed skepticism of the historic accord expressed by some US allies abroad as well as by members of Congress at home, including fellow Democrats.
Israeli Prime Minister Benjamin Netanyahu, one of the fiercest opponents of the six-month deal, called it a "historic mistake" and announced he would be dispatching a top envoy to Washington to try to toughen the final agreement negotiators will soon begin hammering out.
Obama, without naming names, swiped at those who have questioned the wisdom of engaging with Iran.
The weekend agreement between Iran and six world powers the US, Britain, France, Russia, China and Germany is to temporarily halt parts of Tehran's disputed nuclear program and allow for more intrusive international monitoring. In exchange, Iran gains some modest relief from stiff economic sanctions and a pledge from Obama that no new penalties will be levied during the six months.
Despite the fanfare surrounding the agreement, administration officials say key technical details on the inspections and sanctions relief must still be worked out before it formally takes effect.
Iran insists it has a right to enrich uranium for peaceful purposes, and many nuclear analysts say a final deal will almost certainly leave Iran with some right to enrich.
However, that's sure to spark more discord with Israel and many lawmakers who insist Tehran be stripped of all enrichment capabilities. British Foreign Secretary William Hague said he expects the deal to be fully implemented by the end of January.
European Union officials say their sanctions could be eased as soon as December. Those restrictions affect numerous areas including trade in petrochemicals, gold and other precious metals, financial transfers to purchase food and medicine, and the ability of third countries to use EU-based firms to insure shipments of Iranian oil again.
An earlier meeting took place in March, before Iranians elected President Hassan Rouhani, a cleric who has taken more moderate public stances than his predecessor. Details of the secret talks were confirmed to The Associated Press by three senior administration officials.
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