Most of the deceased Pakistani migrants hail from Punjab's districts, including Mandi Bahauddin, Sargodha, Gujrat and Rawalpindi, Dawn reported.
"The four suspects were arrested after the FIA conducted raids in Gujranwala, Gujrat and Mandi Bahauddin," the paper quoted the agency's deputy director as saying.
He said the raids were conducted as part of a crackdown against those involved in human trafficking.
At least 16 Pakistanis were among 90 people drowned off the coast of Libya after a smuggler's boat they were riding capsized last week.
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