A 10-month-old baby and a four-year-old child were diagnosed with the polio virus in Ukraine's southwestern Zakarpattya region, which borders four European Union member states, after paralysis associated with the disease was detected, the Ukrainian health ministry had said on Tuesday.
"It's the first polio case in Europe since 2010," WHO spokesman Oliver Rosenbauer told AFP.
The last case of polio had previously been recorded in Ukraine in 1996, he added.
The two cases are tied to a different type of virus than the one responsible for the 2010 outbreak, said the WHO.
"This means that because of low vaccination coverage, this strain was allowed to circulate in a community as it continued to find susceptible individuals," she said.
Ukrainian deputy health minister Igor Pereginets separately told AFP on Wednesday that a similar polio virus which causes poliomyelitis was detected last year.
Inadequate vaccination puts Ukrainian children at risk of contracting the virus, with only half fully immunised against polio and other vaccine-preventable ailments last year, the Global Polio Eradication Initiative said.
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