Speaking to NBC News in Damascus, the embattled leader insisted his Russian counterpart Vladimir Putin and Foreign Minister Sergei Lavrov had never raised the issue of his departure or a political transition with him.
"Only the Syrian people define who's going to be the president, when to come, and when to go. They never said a single word regarding this," he said.
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Russia and the United States are nominally co-chairs of international efforts to bring Assad's regime to the negotiating table with armed opposition groups.
Hopes for the existing peace process rest on the UN-backed blueprint sketched out by the 22-nation, US and Russian-led International Syria Support Group.
Under this road map, signed by both Syria's ally Iran and Assad's pro-rebel foe Saudi Arabia, a nationwide ceasefire will precede Geneva-based talks on "political transition."
But there has been little progress towards a resumption of political talks that was scheduled for August 1.
A close ally of the government in Damascus, Russia has intervened directly in the conflict since October 2015, when it began air strikes in support of regime forces.
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