The Syrian Observatory for Human Rights said at least four children were among the dead in regime strikes on the rebel-held Eastern Ghouta region, where some 120 people were also injured.
The death toll was likely to rise further, it said.
The air raids hit the towns of Douma, Saqba, Kafr Batna and Hammouriyeh in the rebel stronghold region outside the capital.
An AFP photographer in Douma saw more than a dozen bodies in makeshift plastic shrouds in a field hospital where medical workers struggled to aid the wounded.
Inside a clinic, a young boy wept and hugged his legs -- one roughly bandaged -- as he sat on a blood-smeared floor next to other injured residents.
The strikes came as rebels fired dozens of rockets into Damascus.
The Observatory, without specifying whether the raids or attack on Damascus came first, said at least 13 people, among them 10 civilians, were killed as a barrage of more than 50 rockets slammed into Damascus.
It said another 60 people were wounded.
Rebels often fire into the Syrian capital from rear bases on the outskirts of Damascus, including at times barrages of hundreds of missiles.
Rights groups have condemned indiscriminate rebel rocket fire into the capital as amounting to war crimes.
The government, for its part, regularly carries out air strikes against rebel-held areas on the outskirts of Damascus, particularly Eastern Ghouta which is also under regime siege.
Today, Amnesty International accused the government of war crimes against Eastern Ghouta residents, saying heavy aerial bombardment was compounding misery created by the blockade.
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