Research led by the University of Glasgow and published today in Aging, has found that a moderate increase in serum phosphate levels caused by red meat consumption, combined with a poor overall diet, increases biological age (miles on the clock) in contrast to chronological age (years of age).
The study, which looked at participants from the most deprived to the least deprived in the NHS Greater Glasgow Health Board area, also demonstrates that deprived males were the worst affected.
Researchers believe that excess red meat particularly affects this group because of their poor diet and "sub-optimal fruit and vegetable intake".
The research, led by the Institute of Cancer Sciences in collaboration with the Karolinska Institute (Stockholm, Sweden), also found that high phosphate levels in deprived males correlated with reduced kidney function and even underlying mild to moderate chronic kidney disease.
"The data in this study provides evidence for a mechanistic link between high intake of phosphate and age-related morbidities tied to socio-economic status," Professor Paul Shiels said.
Indeed it's notable that these effects are not apparent among less deprived males, or in females, especially in the context of a more balanced diet.
"Phosphate is naturally present in basic foodstuffs, including meats, fish, eggs, dairy products and vegetables.
Intestinal absorption of naturally occurring phosphate is minimally regulated, as absorption is efficient, hence high supplementation results in markedly elevated levels of serum phosphate, which can have adverse health consequences.
The study, 'Accelerated Ageing and Renal Dysfunction Links Lower Socioeconomic Status and Dietary Phosphate Intake' is published in Aging.
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