The aim is to secure a mammoth deal by July 20 to reduce the programme and ease fears the Islamic republic will get atomic weapons.
Iran denies wanting the bomb and wants punishing UN and Western sanctions lifted.
The parties had "begun the drafting process" and would start the next round of talks on July 2, said a spokesman for EU foreign policy chief Catherine Ashton, who is chief negotiator for the six world powers.
"We presented each other with a number of ideas on a range of issues, and we have begun the drafting process."
Officials on both sides said however that although the drafting process had begun, haggling over language concerning the thorniest problems was being put off until later.
"It has been another really tough round," said a diplomat from one of the "P5+1" six powers late Thursday.
"That doesn't surprise me or particularly dismay me since from the very beginning we have always known that if a deal was to be done, it was going to be very difficult," the envoy said.
"It is worrying that there is no evolution on the part of the Iranians on most subjects," the diplomat told AFP on condition of anonymity, including "major" differences on the key issue of uranium enrichment.
"The talks are being held in a serious and productive atmosphere, but progress in drafting the comprehensive agreement has been limited," one Iranian diplomat told the IRNA news agency.
The trickiest issue is uranium enrichment -- the process of making nuclear fuel for civilian purposes but also, when highly purified, for a nuclear weapon.
Other thorny issues include the duration of the mooted accord, the pace of any sanctions relief and a reactor being built at Arak that might give Iran weapons-grade plutonium.
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