Trump announced the move during his first State of the Union address, reversing his predecessor Barack Obama's decision to close the controversial site "as soon as practicable".
The prison on the American military base at Guantanamo Bay has been used for years to detain high-profile terror suspects and enemy combatants. The facility has been criticised for its grim conditions.
"Terrorists who do things like place bombs in civilian hospitals are evil. When possible, we annihilate them. When necessary, we must be able to detain and question them," Trump said.
Trump rued that in the past the US has "foolishly" released hundreds of dangerous terrorists, only to meet them again on the battlefield -- including the ISIS leader al- Baghdadi.
"So today, I am keeping another promise. I just signed an order directing (Defence) Secretary (James) Mattis to reexamine our military detention policy and to keep open the detention facilities at Guantanamo Bay," Trump said.
The facility has been used since the 9/11 attacks to detain what Washington calls "enemy combatants", but only 41 prisoners remain there.
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