Prosecutor Andrew Edis told a jury that the instruction referred to Calum Best, son of late soccer star George Best, who was the subject of intense interest by the now-defunct Rupert Murdoch-owned tabloid.
Edis was continuing opening arguments in the case against former News of the World editors Coulson and Rebekah Brooks, and six others on hacking-related charges. All deny the allegations.
But prosecutors say Coulson, Brooks and other senior staff must have known that illegal activity was taking place at the paper in the early- to mid-2000s.
Brooks and Coulson, both 45, and six others are on trial in the first major criminal case spawned by the revelation in 2011 that employees of the News of the World eavesdropped on the voice mails of celebrities, politicians and even crime victims.
The phone hacking scandal forced Murdoch to shut the 168-year-old News of the World, triggered several police inquiries and has created intense pressure on Britain's freewheeling tabloid press to mend its ways.
Friends, family and associates of celebrities were also targeted, Edis said, and sometimes even people caught up at random in the tabloid net. He said a hairdresser named Laura Rooney was hacked "because they thought she was related to Wayne Rooney," the Manchester United soccer star. She wasn't.
Three former news editors at the tabloid also have pleaded guilty, but Edmondson denies phone hacking.
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