The UN chief was greeted at the airport by Guinea's foreign and health ministers Francois Louceny Fall and Remy Lamah.
Several officials involved in the drive to end the epidemic in Guinea were also on hand at the airport.
Ban, who did not speak to reporters, was to hold a news conference later today after meeting with Guinean President Alpha Conde.
He was to head next to the Malian capital Bamako to wrap up his tour.
He pledged to help the Ebola-ravaged countries rebuild their health systems.
Ban is accompanied by Margaret Chan, head of the World Health Organisation; David Nabarro, the UN coordinator for the fight against Ebola; and Anthony Banbury, the head of the UN Mission for Ebola Emergency Response or UNMEER.
The Ebola epidemic, which broke out in Guinea in December 2013, has killed more than 6,900 people, almost all of them in west Africa.
The fight to contain the virus has often come up against attitudinal obstacles.
On Friday, hundreds of angry youths prevented the medical aid group Doctors Without Borders (MSF) from setting up an Ebola treatment unit in a southern town, saying they did not want to be infected by the virus.
MSF, which has spearheaded the fight against Ebola, was setting up the unit in Kissidougou, a town in the southern forest near where the outbreak began.
