The coalition strikes hit close by the Turkish frontier, near the town of Tal Abyad just across the border fence from the Turkish town of Akcakale, the Syrian Observatory for Human Rights said.
They came after at least a dozen strikes on Thursday night on the refinery infrastructure that the jihadists have developed in the swathe of territory they control in eastern Syria, which includes many of the country's main oil fields.
"IS had been refining crude and selling it to Turkish buyers," said the Britain-based watchdog, which has a broad network of sources inside Syria.
Before the launch of US-led air strikes on IS in Syria last Tuesday analysts say the jihadists were earning as much as USD 3 million a day from oil revenues.
Output from IS-controlled fields stood at 80,000 barrels per day, far exceeding the 17,000 barrels per day the Syrian oil ministry said it was pumping.
The strikes around Tal Abyad came after yesterday raids on the mainly Kurdish town of Ain al-Arab, also very close to the Turkish border.
The coalition also kept up its raids on the jihadist heartland province of Raqa early today as it pressed what Washington says are "near continuous" strikes.
The raids destroyed a plastics factory outside Raqa city, killing one civilian, the Observatory said.
