An owner of one championship from each of the other three major tournaments, and the French Open runner-up just three weeks ago, Wawrinka was bothered by his left knee and lost 6- 4, 3-6, 6-4, 6-1 to Daniil Medvedev at Centre Court in the first round at the All England Club last night.
Wawrinka was seeded No. 5 and ranked No. 3. He iced his knee during changeovers and never was able to summon his best tennis.
He said his knee has been a problem off and on this season, including at the Australian Open in January, when he made a run to the semifinals.
Wawrinka said he was a bit hesitant about even playing at Wimbledon, but he thought the knee seemed better during recent practices.
He had no answers when asked what comes next, including how much time he might need to take off.
Wawrinka won the Australian Open in 2014, the French Open in 2015 and the US Open in 2016. But he never has been able to excel at the All England Club, where his best showing is getting to the quarterfinals and his career record is now 18- 13.
This was Wawrinka's sixth defeat in the first round at Wimbledon.
And just how big a victory was this for Medvedev, a 21- year-old Russian who is ranked 49th?
He dropped to his knees and kissed the Centre Court turf afterward.
"So even, I guess, if I didn't beat Stan, it would be one of the biggest wins in my life. My first top-10 win. I have no words to describe this," Medvedev said. "I guess this memory will be with me forever.
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