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An exposure to high temperatures during pregnancy could be disrupting amino acids and vitamins key to managing stress and energy, thereby increasing the risk of a premature delivery, suggests an analysis of blood samples. Studies have observed a link between warmer ambient temperatures and preterm births, where a baby is born before 37 weeks of pregnancy. The analysis, published in the journal Science Advances, looked at small molecules or "molecular fingerprints" in blood samples of 215 pregnant women who were residents of the US metropolitan city of Atlanta, and matched residential addresses with the maximum ambient temperatures experienced throughout their pregnancies. The first-of-its-kind study by researchers at Emory University found a disruption in levels of naturally occurring substances in blood, such as methionine, proline, citrulline and pipecolate, when ambient temperatures were higher. Methionine is an essential amino acid, obtained through diet, while citrulline is a
India has witnessed a significant improvement in key maternal and child health indicators between 2014 and 2021, according to a Health Ministry statement. The Maternal Mortality Ratio (MMR) has declined by 37 points from 130 per lakh live births in 2014-16 to 93 in 2019-21, the statement mentioned, citing the Sample Registration System (SRS) Report 2021 released by the Registrar General of India (RGI) on Wednesday. Similarly, the downward trend of child mortality indicators continued. The Infant Mortality Rate (IMR) has dropped from 39 per 1000 live births in 2014 to 27 per 1000 live births in 2021. The Neonatal Mortality Rate (NMR) has declined from 26 per 1000 live births in 2014 to 19 per 1000 live births in 2021. Under-Five Mortality Rate (U5MR) has also improved, dropping from 45 in 2014 to 31 per 1000 live births in 2021. The Sex Ratio at Birth also improved between 2014 and 2031, getting better from 899 to 913, respectively. Total Fertility Rate is consistent at 2.0 in 2021
A woman died and four others were critical after delivery of babies at the Midnapore Medical College and Hospital (MMCH), an official said on Saturday. The family members of the deceased woman alleged that Ringer's Lactate administered on the intravenous (IV) fluid had expired and it was responsible for her death. They have lodged a complaint at the Kotwali police station. The woman died on Friday after delivery of her baby on Wednesday, he said. After the death of a woman and the deterioration in the health conditions of four other women, the state health department has formed a 13-member panel to investigate the matter, following a police complaint lodged with the Kotwali police station by the husband of the deceased, the official said. "There is a death of a woman in Midnapore Medical College and Hospital. There are a few who are also critical. The family members have alleged that the Ringer's Lactate (RL) administered on the Intravenous (IV) fluid has expired. We have received
Pharma major Lupin Ltd on Friday said it has received approval from the US health regulator to market its generic 'Minzoya' tablets used to prevent pregnancy. The approval granted by the US Food and Drug Administration (USFDA) is for the abbreviated new drug application for Minzoya (Levonorgestrel and Ethinyl Estradiol tablets, and Ferrous Bisglycinate tablets) of strengths 0.1 mg/0.02 mg and 36.5 mg, Lupin said in a regulatory filing. The drug is a generic equivalent of Balcoltra (Levonorgestrel and Ethinyl Estradiol Tablets, USP and Ferrous Bisglycinate Tablets) 0.1 mg/0.02 mg and 36.5 mg, of Avion Pharmaceuticals LLC, it added. The product will be manufactured at Lupin's Pithampur facility in India, the company said. Minzoya tablets are indicated for use by females of reproductive potential to prevent pregnancy. Levonorgestrel and Ethinyl Estradiol tablets, and Ferrous Bisglycinate tablets had estimated annual sales of USD 42 million in the US, the company said citing IQVIA MAT