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After a long wait, the Senate is launching action on President Donald Trump's "big, beautiful bill of tax breaks and spending cuts at a risky moment for the U.S. and global economy. More than a month after House Republicans surprised Washington by advancing their framework for Trump's tax breaks and spending cuts package, Senate Republicans voted Thursday to start working on their version. The 52-48 vote sets the stage for back-to-back Senate all-nighters spilling into Friday and the weekend. But work on the multitrillion-dollar package is coming as markets at home and abroad are on edge in the aftermath Trump's vast tariffs scheme, complicating an already difficult political and procedural undertaking. Senate Majority Leader John Thune, R-S.D., opened the chamber Thursday saying they were expected to begin as soon as today embarking on what they hope will become the GOP's signature domestic policy package. Trump says he's on board and Republicans, in control of Congress, are eager