Luis Enrique will be looking for a response after Spain endured a disappointing end to their Nations League campaign at the end of last year, when losses to England and Croatia saw them miss out on the semi-finals.
Navas has not appeared for the national team since October 2013 but the former Manchester City winger has been in excellent form for Sevilla this season. Alvaro Morata was also included following his strong start at Atletico and was joined by fellow forwards Marco Asensio, Rodrigo, Muniain and Mata. Diego Costa and Iago Aspas are both injured.
Goalkeepers: David de Gea, Kepa Arrizabalaga, Pau Lopez Defenders: Jesus Navas, Sergi Roberto, Sergio Ramos, Mario Hermoso, Inigo Martinez, Jose Gaya, Jordi Alba, Juan Bernat Midfielders: Sergio Busquets, Rodrigo, Dani Ceballos, Fabian Ruiz, Dani Parejo Forwards: Marco Asensio, Rodrigo, Alvaro Morata, Iker Muniain, Jaime Mata.