In a tweet, Panneerselvam hailed Hawking as an "extraordinary person", a "great scientist" and an "unforgettable" person.
"Stephen Hawking's demise is an irreparable loss for mankind," he added.
Haasan, founder of the Makkal Neethi Maiam (MNM) said people all over the world would be proud that Hawking lived among them.
"We shall forever remember his knowledge grant. His fame shall live (forever)," the actor-politician said in a tweet.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)