Police said Saturday that the two traffickers, including the 24-year-old Iraqi driver, were among the injured.
The van, with Bulgarian license plates, failed to stop at a police checkpoint.
The driver exited the highway at high speed and collided with a truck late Friday about 80 kilometers (50 miles) east of Thessaloniki.
The Greek truck driver wasn't injured.
Smuggling gangs charge high fees to squeeze migrants into small vehicles at the border with Turkey and carry them to Thessaloniki, and accidents are frequent.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)