Wall Street ends down after White House shakeup

NEW YORK (Reuters) - U.S. stocks closed lower after another volatile session on Friday as the latest White House shake-up kept investors jittery about the outlook for the Trump agenda.

The Dow Jones Industrial Average <.DJI> fell 76.22 points, or 0.35 percent, to 21,674.51, the S&P 500 <.SPX> lost 4.46 points, or 0.18 percent, to 2,425.55 and the Nasdaq Composite <.IXIC> dropped 5.39 points, or 0.09 percent, to 6,216.53.

(Reporting by Caroline Valetkevitch; Editing by Nick Zieminski)