The Dow Jones Industrial Average <.DJI> slumped 755.87 points, or 3.45%, to 21,161.29, the S&P 500 <.SPX> lost 89.48 points, or 3.46%, to 2,495.11 and the Nasdaq Composite <.IXIC> dropped 209.88 points, or 2.73%, to 7,490.22.
"President Trump's warning about two dreadful weeks ahead and 100,000 - 240,000 deaths in the coming months is definitely putting a negative tone on the market," said Societe Generale strategist Kit Juckes. "It is pretty risk-off out there. It is definitely a day of lower bonds yields, falling equity indexes and tin hats."
U.S. markets ended the first quarter on Tuesday, marked by the largest quarterly fall since 1987 for the Dow Jones and the steepest for the benchmark S&P 500 since the financial crisis. The fact it all happened in a month and from record highs made it feel all the more brutal.