The study estimates that around 470,000 people die each year because of human-caused increases in ozone.
It also estimates that around 2.1 million deaths are caused each year by human-caused increases in fine particulate matter (PM2.5) - tiny particles suspended in the air that can penetrate deep into the lungs, causing cancer and other respiratory disease.
"Our estimates make outdoor air pollution among the most important environmental risk factors for health. Many of these deaths are estimated to occur in East Asia and South Asia, where population is high and air pollution is severe," study co-author, Jason West, from the University of North Carolina, said.
According to the study, published in journal Environmental Research Letters, the number of these deaths that can be attributed to changes in the climate since the industrial era is, however, relatively small.
It estimates that a changing climate results in 1500 deaths due to ozone and 2200 deaths related to PM2.5 each year.
Climate change affects air pollution in many ways, possibly leading to local increases or decreases in air pollution, researchers said.
Higher temperatures can also increase the emissions of organic compounds from trees, which can then react in the atmosphere to form ozone and particulate matter.
"Very few studies have attempted to estimate the effects of past climate change on air quality and health. We found that the effects of past climate change are likely to be a very small component of the overall effect of air pollution," said West.
Researchers used an ensemble of climate models to simulate the concentrations of ozone and PM2.5 in the years 2000 and 1850. A total of 14 models simulated levels of ozone and six models simulated levels of PM2.5.
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