Emma Coronel told the US Spanish-language Telemundo yesterday that Guzman is an intelligent and affectionate man, and that she had no proof that he was in the drug trade.
"The Mexican government made sure to portray Joaquin Guzman as the world's most wanted kingpin -- that doesn't mean that he turned into the world's most wanted kingpin," said Coronel, 26.
"I don't know if they did it on purpose or to cover up more important things, because the things they are bringing out and saying seems highly exaggerated."
"El Chapo" was recaptured on January 8, six months after he tunneled his way out of a maximum security prison.
He was returned to the same prison he escaped from, the Altiplano, some 90 kilometres west of Mexico City.
Coronel denied that Guzman was one of the world's richest men, and said she had no idea where the billions of dollars Guzman allegedly has are located.
"I don't know where they get that he is bloodthirsty, even a rapist," she said. "It seems very unjust to be saying such outrageous things about him."
To prevent another escape, prison authorities at the Altiplano assigned two permanent guards in front of his cell, with a camera on top of their helmets to watch his every move. They also regularly move Guzman to a new cell without warning.
A dog also tastes his food before it is served to him to thwart any poisoning attempt.
Guzman and Coronel were reportedly married in 2007 in the northern state of Durango, when she was 18 years old.
Coronel said she feared for her 61-year-old husband's life, saying that he's being mistreated in prison as payback for embarrassing the government by escaping last year.
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