After a ceremony in the village of Le Vernet, about 80 of them will make a grueling pilgrimage to the crash site at an altitude of some 1,500 metres.
Aided by volunteer firefighters and mountain guides, they will walk a muddy, snow-covered mountain path, much of it carved out to allow emergency workers to access the site.
A red stake planted in the soil marks the exact site where the plane went down, killing all 150 people on board.
Yesterday a young German woman had already made a six-hour journey to the site.
Her daughter was one of a group of high school students who were killed in the crash.
"At first, I didn not think I would ever fly again," she said, asking not to be named.
Investigations found that Lubitz had a history of depression and suicidal tendencies and the case has raised questions about medical checks faced by pilots as well as doctor-patient confidentiality.
After the tragedy, the European Aviation Safety Agency (EASA) recommended that airlines ensure at least two crew members, including at least one qualified pilot, are in the flight crew compartment at all times.
Top managers of Lufthansa -- the parent company of the lowcost Germanwings airline -- arrived in Le Vernet to take part in the commemoration ceremony.
The company -- which has denied any wrongdoing -- is facing a lawsuit in the United States from family members who argue Lubitz should not have been allowed to fly.
"Today is not the day to talk about legal issues, today we are just here, with 100 Lufthansa employees, to help the families and support them in their grief."
The ceremony will begin with the reading of the names of the 149 victims in front of a headstone erected in their memory, with a minute of silence at 0941 GMT, the exact time of the crash.
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