Lennon, 45, has previously collaborated with Perry for 2009 film "17 Again". He says their relationship on "Odd Couple" is similar to the camaraderie they share in real life.
"Our on-screen and off-screen chemistry is almost identical. We have known each other for a long time. I did 'Friends' with him, then '17 again'. I have known him for almost 15-20 years. We get along pretty well. I hope people really enjoy watching us on the show," Lennon told PTI.
It is the sixth screen production based on the 1965 play of the same name, written by Neil Simon.
"I think in many ways it is an old-fashioned show. The show is a classic. It is lot of fun."
"The Odd Couple" season 1 and 2 is set to air in India from June 23 on Star World.
When asked what aspect of the show will click with the Indian audience, Lennon said, "I think every audience around the world has met people like our characters in their lives.
Lennon, best known for his roles in "Bad Teacher", "Memento", "How To Lose A Guy In 10 Days", "Transformers: Age of Extinction" and "I Love You, Man", said he loves doing comedies as opposed to dramas as he gets to see the audience's reaction instantly.
"We film in front of a live audience every Tuesday night. We get to know if we succeeded or not. When you do a dramatic role then you don't get to see the reaction and unable to see whether the show is going well or not."
Lennon and Garant are working on a new action-comedy "The Revenger", which is being directed by Ruben Fleischer and stars Liam Neeson.
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