"The decision to proceed with a vaccination campaign was taken after it was found that between 1,000 and 2,000 people living in southern Israel are carriers of the virus, without themselves being sick," she told Channel 2 television.
"We have already ordered 5,00,000 doses of vaccine from abroad and are ready to order 5,00,000 more if necessary in the coming weeks," German said.
She said the entire population could be vaccinated if the measures taken in the south do not prevent polio cases from appearing elsewhere.
Channel 2 also reported that a World Health Organisation representative will be involved in the vaccination campaign starting tomorrow.
Media reports said the polio virus had been detected in sewage at communities in the south.
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