Victory would take Argentina into the last four -- where either Holland or Costa Rica will await -- for only the second time since they last won the tournament in 1986, beating Belgium in the semi-finals en route.
But despite results living up to expectations -- Argentina have won all four of their games to date -- performances have not, and the team's dependence on Messi has been cited as the key factor.
Diego Maradona was scathing of the team's performance, warning coach Alejandro Sabella that he is destined for "catastrophe" if he cannot alleviate some of the burden on the team's outstanding player.
Argentina's assault on the World Cup was supposed to be spearheaded by their 'Fantastic Four' attackers, but Messi is the only one who has lived up to his billing so far.
Facing accusations that his side are overly reliant on their number 10, Sabella said that "Argentina have always had a dependence on Messi".
It is likely to be no different against Belgium and Messi's task will be rendered doubly difficult by the fact that the opposition goalkeeper, Thibaut Courtois of Atletico Madrid, has kept him at bay for seven games in succession.
