The show is produced by Hall and Coben, reported Entertainment Weekly.
The 46-year-old actor was the star of Showtime series "Dexter" from 2006 to 2013, and in "Safe" will play a British paediatric surgeon raising two teenage daughters, Jenny and Carrie, alone after the death of his wife.
The family is seemingly safe inside a gated community when the elder daughter sneaks out to a party and a murder and disappearance follow, changing all of their lives.
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