The suicide bomber, who targeted shops and food stands near a bus station in the city's busy Bab al-Muadam area, killed 11, a police officer said. He says the bombing also wounded at least 22 people.
Earlier in the day, bombings elsewhere in and around Baghdad killed at least 16 people and wounded dozens, officials said.
A medical official confirmed the casualty figures. All officials spoke on condition of anonymity as they were not authorised to release information.
Earlier today, a car bomb tore through a Baghdad market, killing nine people while four other attacks mostly by bombs that went off in commercial areas or targeted security forces killed at least seven.
In the Baghdad market attack, the car bomb was parked near outdoor fruit and vegetable stalls in a mostly Shiite neighborhood.
The fatalities included two policemen. The Sunni extremists frequently target Iraq's security forces and civilians in Shiite neighborhoods.
Mosul, about 360 kilometers northwest of Baghdad, is the extremist group's last major urban bastion in the country. Iraqi forces have retaken around a quarter of the city since the offensive began.
Iraq announced a new operation today to recapture IS-held towns near the Syrian border.
Maj Gen Qassim al-Mohammadi said the troops would try to dislodge IS from Rawah, Anah and Qaim, towns in the western Anbar province that fell to the extremists in the summer of 2014.
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