The move, which would expand an already existing system of self-administration, is likely to anger Turkey which is wary of any bid by Syrian Kurds to solidify their autonomy and of their control of territory.
Kurdish groups, which hold large stretches of northern Syria, have been excluded from ongoing peace talks in Geneva aimed at ending the country's five-year conflict.
More than 150 delegates from Kurdish, Arab, Assyrian and other parties were meeting today in the town of Rmeilan, in Syria's northeastern Hasakeh province.
"All the suggestions are now heading towards federalism," he told AFP from the conference.
Officials said the conference's final decision would be issued either today or tomorrow.
Kurdish parties already operate a system of three "autonomous administrations" in Syria's north, with independent police forces and schools.
The three cantons run along Syria's northern border with Turkey and are known as Afrin and Kobane, both in Aleppo province, and Jazire in Hasakeh province.
Officials said the announcement was not intended as a first step towards independence.
"A federal state for ruling all of Syria is the best way to protect Syria from being divided up, because there is major distrust among the different sides," said Ibrahim Ibrahim, a PYD media official.
Washington-based analyst Mutlu Civiroglu said the announcement would be a political message "from Syrians on the ground, politically and militarily".
Despite deep divisions, the opposition High Negotiations Committee and the embattled government in Damascus have both categorically rejected a federal system in Syria.
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