Scientists said initial sampling suggests the burger will not taste great, but it is expected to be "good enough".
Researchers took cells from a cow and, at an institute in the Netherlands, turned them into strips of muscle which they combined to make a patty.
They claim the technology could be a sustainable way of meeting what they say is a growing demand for meat, 'BBC News' reported.
"Later today we are going to present the world's first hamburger made in a lab from cells. We are doing that because livestock production is not good for the environment, it is not going to meet demand for the world and it is not good for animals," said Professor Mark Post of Maastricht University, the scientist behind the burger.
Three weeks later, there are more than a million stem cells which are put into smaller dishes where they coalesce into small strips of muscle about a centimetre long and a few millimetres thick.
These strips are collected into small pellets which are frozen. When there are enough, they are defrosted and compacted into a patty just before being cooked.
The scientists have tried to make the meat - which is initially white in colour - as authentic as possible.
"If it doesn't look like normal meat, if it doesn't taste like normal meat, it's not going to be a viable replacement," Breewood told the BBC.
Currently, this is a work in progress. The burger to be revealed today will be coloured red with beetroot juice. The researchers have also added breadcrumbs, caramel and saffron, to add to the taste.
Breewood, a vegetarian herself, said she would eat lab-grown meat.
"A lot of people consider lab-grown meat repulsive at first. But if they consider what goes into producing normal meat in a slaughter house I think they would also find that repulsive," she said.
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