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Shorter duration of radiation safe in treating prostate cancer: Study

IANS  |  New York 

Men with low or intermediate-risk prostate can safely undergo higher doses of over a significantly shorter period of time and still have the same, successful outcomes as from a much longer course of treatment, according to researchers including one of Indian-origin.

The study showed that this type of - - is a form of external beam therapy, which reduces the duration of treatment from 45 days to four to five days with no evidence of causing worse toxicity in the long run.

"Most men with low or intermediate-risk prostate undergo conventional radiation, which requires them to come in daily for treatment and takes an average of nine weeks to complete," said Amar Kishan, at University of California, Los Angeles, in the US.

"With the improvements being made to modern technology, we have found that using stereotactic body radiotherapy, which has a higher dose of radiation, can safely and effectively be done in a much shorter timeframe without additional toxicity or compromising any chance of a cure," said Kishan.

For the study, the team included 2,142 men with low or intermediate-risk prostate who were treated with They were followed for a median of 6.9 years.

Nearly, 53 per cent men had low-risk disease, 32 per cent had less disease and 12 per cent had a more aggressive form of

In addition, the recurrence rate for men with was 4.5 per cent, 8.6 per cent for the less aggressive intermediate-risk, and 14.9 per cent for the more group, findings published in the journal JAMA Network Open showed.

Overall, the recurrence rate for was 10.2 per cent.

These are essentially identical to rates following more conventional forms of radiation, which are about 4-5 per cent for and 10 per cent to 15 per cent for

This method is both safe and effective and could be a viable treatment option for men with low and intermediate-risk of prostate cancer, the study suggested.



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sat, February 09 2019. 13:14 IST