MPs have warned that unless Cameron led a campaign to keep Britain within the economic bloc won with a decisive majority, his future as Prime Minister would be on the line.
"If remain win by a narrow majority, or if leave win, he's toast within days," Tory MP Nadine Dorries told ITV channel in an interview yesterday.
"The party is fairly fractured, straight down the middle and I don't know which character could possibly pull it back together going forward for an effective government. I honestly think we probably need to go for a general election before Christmas and get a new mandate from the people," Bridgen said.
He also claimed that at least 50 Tory MPs, the number needed to call a confidence vote felt the same way about Cameron and that a vote on the Prime Minister's future was "probably highly likely" after the referendum.
"It's shameful that those leading the pro-EU campaign fail to care for those who do not have their advantages".
Meanwhile, Cameron kept up the momentum of his campaign against Brexit and is even set to share the stage with newly-elected London mayor Sadiq Khan -- from the Opposition Labour party today.
He said: "Is it in London's interest for me to hold grudges? Is it in London's interests for the mayor of London to be at permanent war with the Conservative prime minister? We're never going to be best friends, but what is important is that the mayor of London argues the case for London and for Londoners to remain in the European Union.
"This debate is far more important than David Cameron or me. It's about our city's future and country's future".
Khan and Cameron jointly launched a 'Britain Stronger In Europe' battle bus in London, despite Labour leader Jeremy Corbyn refusing to campaign with Cameron.
Cameron congratulated Khan on his victory in the Mayoral contest, saying, "I'm proud to be here with the mayor of London - with the Labour mayor of London - on this vital, vital issue.
He hailed the fact that "someone who is a proud Muslim, a proud Briton and a proud Londoner can become mayor of the greatest city on Earth."
"That says something about our country," Cameron said.
He said he expected many disagreements with the London Mayor but they were both part of "an incredibly broad campaign" in favour of EU membership.
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