Rescuers had feared there could be bodies trapped under the rubble of the heavily damaged office block, but the city's mayor said nobody was believed to have been killed.
The force of the explosion damaged parked cars and two adjacent university buildings, blew out windows in nearby streets, and shook apartment blocks across the Vltava river.
"It was a gas blast, not a terror attack," Prague mayor Bohuslav Svoboda told reporters.
He added that "they haven't found anyone (in the rubble)... And nobody is reported missing".
"Everyone was running, the blast toppled the bookshelves in the library. In one classroom there were lots of injured students, the librarians had blood on their T-shirts," she added.
"At one department the blast wave broke a window on one side and warped the door on the other so people couldn't get out and had to kick the door open."
Forty-three people were injured, including two Kazakhs, two Portuguese, one German and one Slovak, said Zdenek Schwarz, head of Prague emergency services.
An AFP photographer at the scene saw dozens of people with cuts from shattered glass from windows along the debris-strewn Divadelni Street.
Injured victims were treated on the spot for cuts, some with blood streaming down their faces and bandages on their heads and many of them in shock.
Jan Hora, a structural engineer, told Czech TV the damaged building -- a former block of flats now used as office space -- had to be supported with poles but would probably not collapse.
You’ve reached your limit of {{free_limit}} free articles this month.
Subscribe now for unlimited access.
Already subscribed? Log in
Subscribe to read the full story →
Smart Quarterly
₹900
3 Months
₹300/Month
Smart Essential
₹2,700
1 Year
₹225/Month
Super Saver
₹3,900
2 Years
₹162/Month
Renews automatically, cancel anytime
Here’s what’s included in our digital subscription plans
Exclusive premium stories online
Over 30 premium stories daily, handpicked by our editors


Complimentary Access to The New York Times
News, Games, Cooking, Audio, Wirecutter & The Athletic
Business Standard Epaper
Digital replica of our daily newspaper — with options to read, save, and share


Curated Newsletters
Insights on markets, finance, politics, tech, and more delivered to your inbox
Market Analysis & Investment Insights
In-depth market analysis & insights with access to The Smart Investor


Archives
Repository of articles and publications dating back to 1997
Ad-free Reading
Uninterrupted reading experience with no advertisements


Seamless Access Across All Devices
Access Business Standard across devices — mobile, tablet, or PC, via web or app
