Seeded third, Saina went down 15-21 19-21 to her lower ranked opponent in just 39 minutes in Kowloon.
Before today's match, Saina held a 5-2 edge over her Taipei rival. Last time the two met, the Indian had defeated Ying in the semifinals of Swiss Open in 2013.
World No. 4 Saina, who recently won the title at China Open, looked pretty rusty today.
Breaking away from a 2-2 tie in the first game, there was no looking back for the Taipei girl. She just kept on extending the lead, even as Saina played the catch-up game.
Although Saina tried her best, she always trailed behind Ying, seeded sixth. By the end of the opening round, the Taipei girl had surged ahead wrapping it up 21-15.
The Olympic bronze medallist, however, pulled up her socks in the second game and came up with a much-improved show.
