"Police were called to reports of an explosion at Manchester Arena. So far, 19 people have been confirmed dead with around 50 others injured," Greater Manchester Police said in a statement.
"This is currently being treated as a terrorist incident until police know otherwise," the statement added.
Eyewitnesses reported hearing a loud "bang" from inside the venue, which was playing host to a concert by American pop star Ariana Grande. Video footage from the scene showed bloodied victims being helped by emergency services.
Watch as people at the concert panic after the blast
Video courtesy: The New York Times