Women with endometriosis, especially those under 40, are at increased risk for cardiovascular disease, a new study has found.
Endometriosis, the growth of uterine tissue outside the uterus, may affect as many as 10 per cent of women in their reproductive years. It can cause pelvic pain, painful menstruation, painful sexual intercourse and reduced fertility. The analysis, in Circulation: Cardiovascular Quality and Outcomes, included 116,430 women free of heart disease and stroke at the start of the study. By the end of a 20-year follow-up period, 11,903 of the women had been given a diagnosis of endometriosis.
After adjustment for pregnancies, alcohol intake, physical activity, body mass index, diabetes and more than a dozen other factors, they found that women with endometriosis were 52 per cent more likely to have had a heart attack, 91 per cent more likely to have had angina and 35 per cent more likely to have undergone coronary surgery. This was a prospective study with a large sample and a long follow-up, factors which give it considerable strength.