The double-amputee killed Reeva Steenkamp, a model and law graduate, in the early hours of Valentine's Day in 2013, saying he mistook her for an intruder when he fired four times through the door of his bedroom toilet.
Looking tired and sometimes resting his head in his hands, the 29-year-old "Blade Runner" attended the first day of the sentencing hearing at the High Court in Pretoria along with members of his family.
"Further imprisonment would have a detrimental effect on him as a person, considering his current clinical condition."
Scholtz said that during recent interviews Pistorius had displayed signs of "post-traumatic stress disorder, anxiety disorder and depressive disorder".
"Currently he is not able to testify. His condition is severe," he said.
In March, Pistorius's lawyers failed in their legal bid to reverse a Supreme Court of Appeal judgement that upgraded his original conviction from culpable homicide-the equivalent of manslaughter-to murder.
Scholtz added that Pistorius "has almost given up, his spirit seems broken" and he should be sent to hospital.
"(He is) a vulnerable, anxious man, extremely uncertain of himself without his prostheses."
Pistorius faces a minimum 15-year jail term for murder, but his sentence could be reduced due to time already spent in prison and mitigating factors, including his disability.
Steenkamp's parents were both in court today, and her father Barry may take the witness stand to ask the court to impose a lengthy punishment.
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