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Prevalence of hypertension or high blood pressure among children and teenagers has nearly doubled in the last two decades, from 3.2 per cent in 2000 to over six per cent in 2020, according to a global analysis published in The Lancet Child and Adolescent Health journal. Left unaddressed, hypertension can lead to cardiovascular and kidney disease. Estimates also suggest that nearly a fifth of the world's children and adolescents with obesity have hypertension -- about eight times the prevalence among those having a healthy weight (2.4 per cent), researchers including those from the UK's University of Edinburgh said. The findings suggest obesity is a substantial driver of the increase in childhood hypertension. Obesity tends to cause other issues, such as insulin resistance and changes in blood vessels, which can make it harder to maintain a healthy blood pressure. Further, eight per cent of children and teenagers around the world may be having pre-hypertension, which is a warning si
Alembic Pharmaceuticals on Friday said it has received final approval from the US health regulator for its generic version of amlodipine and atorvastatin tablets, used to treat high blood pressure. The final approval by the US Food & Drug Administration (USFDA) is for the abbreviated new drug application (ANDA) of Amlodipine and Atorvastatin tablets of strengths 2.5 mg/10 mg, 2.5 mg/20 mg, 2.5 mg/40 mg, 5 mg/10 mg, 5 mg/20 mg, 5 mg/40 mg, 5 mg/80 mg, 10 mg/10 mg, 10 mg/20 mg, 10 mg/40 mg, and 10 mg/80 mg, the company said in a statement. These are therapeutically equivalent to the reference-listed drug product, Caduet tablets of corresponding strengths of Pharmacia and Upjohn Co LLC, it added. Alembic said it has a cumulative total of 223 ANDA approvals (199 final approvals and 24 tentative approvals) from the USFDA.
Men in many countries are more likely to fall sick and die from hypertension, diabetes, and HIV/AIDS as compared to women, according to a new study. However, compared to women, men were found to be less likely to seek medical care and adhere to treatment for these common health conditions due to norms related to masculinity and healthcare financing. Men were also more likely to smoke, while women were more likely to be obese and engage in unsafe sex, the study, published in the journal PLOS Medicine, found. The research highlights sex-based differences at each step of the "health pathway", which includes being exposed to a risk factor -- such as smoking -- developing a condition, diagnosis, treatment and death, study authors said. "Most of these differences are not explained by sex (biology) alone, but by socially-constructed gender -- highlighting the importance of taking a gender justice approach to reducing health inequities. A gender analysis can help to shape systems of health
Alembic Pharmaceuticals Ltd on Monday said it has received final approval from the US health regulator for its generic Diltiazem Hydrochloride extended-release capsules indicated for the treatment of hypertension. The approval by the US Food & Drug Administration (USFDA) for the abbreviated new drug application (ANDA) for Diltiazem Hydrochloride Extended-Release Capsules of strengths 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg, Alembic Pharmaceuticals Ltd (Alembic) said in a statement. These capsules are indicated for the treatment of hypertension. These capsules may be used alone or in combination with other antihypertensive medications. Moreover, Diltiazem Hydrochloride is also indicated for the management of chronic stable angina and angina due to coronary artery spasm, the company said. Diltiazem Hydrochloride extended-release capsules 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg have an estimated market size of USD 105.3 million for the 12 months ended June 2024, the company ...
The prevalence of diabetes in India is 11.4 per cent, while 35.5 per cent of people suffer from hypertension, according to the findings of a nationwide survey published in The Lancet Diabetes & Endocrinology journal. The study, conducted by the Madras Diabetes Research Foundation in collaboration with the Indian Council of Medical Research (ICMR) and other institutes, also found that the prevalence of generalised obesity and abdominal obesity in India stood at 28.6 and 39.5 per cent, respectively. The results, assessing the burden of non-communicable diseases (NCD) across the states, are based on a survey of 1,13,043 (over 1.1akh) people (33,537 urban and 79,506 rural residents), in 31 states and Union Territories in the country, between 2008 and 2020. The survey also showed that 35.5 per cent of Indians suffer from hypertension, 15.3 per cent of people have pre-diabetes, while an alarming 81.2 per cent have dyslipidaemia -- the imbalance of lipids such as cholesterol, low-density