So, will this mutation in BA.2.12.1 lead to pulmonary infections, which were common during the second Covid wave led by the Delta variant?
The Omicron sub-lineage BA.2.12.1, which is causing a surge in Covid-19 cases in the National Capital Region (NCR), has a mutation in the spike protein similar to the one found only in the Delta lineage. Whether this causes any severity in infections is to be seen, but so far, clinicians claim, most Covid-positive cases are asymptomatic or mild.
Speaking to Business Standard, Shahid Jameel, senior research fellow at Green Templeton College at Oxford University, said Omicron now has two main lineages – BA.1 and BA.2, both with several sub-lineages. “As a group, BA.2 spreads about 20 per cent better than BA.1,” he said.
“There are two key mutations in the spike (protein) in BA.2.12.1 that are missing from BA.2.12 and
First Published: Apr 23 2022 | 06:10 AM IST