Explore Business Standard
Cardiovascular diseases remain the leading cause of mortality in India, causing nearly 31 per cent of deaths, according to the latest data presented by the Sample Registration Survey under the Registrar General of India. The Report on Causes of Death: 2021-2023, issued on Wednesday, said non-communicable diseases are the leading causes of death in the country, constituting 56.7 per cent of all deaths. "Communicable, maternal, perinatal and nutritional conditions constitute another 23.4 per cent of deaths. In the 2020-2022 (affected by COVID) period, the corresponding values were 55.7 per cent and 24.0 per cent, respectively," it said. The report said that overall cardiovascular disease remained the leading cause of death, claiming nearly 31 per cent of lives, followed by respiratory infections at 9.3 per cent, malignant and other neoplasms at 6.4 per cent, and respiratory diseases at 5.7 per cent. The cardiovascular diseases, a lifestyle phenomenon, are the leading cause in the ...
Pharma firm Caplin Point Laboratories Ltd on Wednesday said its arm Caplin Steriles Ltd has received final approval from the US health regulator for its generic milrinone lactate in 5 per cent dextrose injection indicated for the short-term intravenous treatment of patients with acute decompensated heart failure. The approval granted by the US Food and Drug Administration (USFDA) is for the abbreviated new drug application (ANDA) milrinone lactate in 5 per cent Dextrose Injection of strengths 20 mg/100 mL and 40 mg/200 mL in single-dose infusion bags, Caplin Point Laboratories said in a regulatory filing. The approved injection is a generic therapeutic equivalent version of the reference listed drug PRIMACOR in dextrose 5 per cent, by Sanofi Aventis US LLC, it added. Milrinone is indicated for the short-term intravenous treatment of patients with acute decompensated heart failure, the company said. Citing IQVIA (IMS Health) data, the company said milrinone lactate in 5 per cent ...
Researchers have discovered how COVID-19 infection damages the heart tissue, paving the way for better treatments for the condition. The study conducted on a small group of people found that COVID-19 damaged the DNA in heart tissue, which was not detected in influenza samples. The researchers noted that while COVID-19 and influenza are both severe respiratory viruses, they appeared to affect cardiac tissue very differently. "In comparison to the 2009 flu pandemic, COVID has led to more severe and long-term cardiovascular disease but what was causing that at a molecular level was not known," said Arutha Kulasinghe from the University of Queensland, Australia. "During our study, we couldn't detect viral particles in the cardiac tissues of COVID-19 patients, but what we found was tissue changes associated with DNA damage and repair," Kulasinghe said. DNA damage and repair mechanisms are related to chronic diseases such as diabetes, cancer, atherosclerosis and neurodegenerative disord