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UK plans to mix coronavirus vaccines

Britain is planning to administer different vaccine shots for first and second doses, a move experts say is not unreasonable but should be backed by rigorous investigations. According the guidelines, different vaccines will be given in rare cases where the same vaccine is not available or it is not known what vaccine the patient received. The move is based on the theory that two approved candidates from Oxford and Pfizer target the spike protein of the virus, which makes it likely that the second dose will help boost the response to the first, and would