| National Stadium Karachi ODI stats | |
| Statistic | Detail |
| Total Matches | 79 |
| Matches Won Batting 1st | 37 |
| Matches Won Chasing | 39 |
| Average 1st Innings Score | 240 |
| Highest Total | 374/4 (50 ovs) by India vs Hong Kong in 2008 |
| Lowest Total | 115 (38.2 ovs) by Bangladesh vs Pakistan in 2008 |
| Highest Successful Chase | 355/4 (49 ovs) by Pakistan vs South Africa in 2025 |
| Lowest Total Defended | 146 (43.3 ovs) by Pakistan vs New Zealand in 1994 |
| Most Runs | Mohammad Yousuf (Pakistan) - 817 |
| Highest Individual Score | Viv Richards (West Indies) - 181 |
| Most Sixes | MS Dhoni (India), Sanath Jayasuriya (Sri Lanka), Mohammad Yousuf (Pakistan) - 12 |
| Most 50s | Mohammad Yousuf (Pakistan), Younis Khan (Pakistan) - 6 |
| Most 100s | Suresh Raina (India), Kumar Sangakkara (Sri Lanka), Babar Azam (Pakistan), Sanath Jayasuriya (Sri Lanka), Salman Butt (Pakistan), Mohammad Yousuf (Pakistan) - 2 |
| Most Wickets | Wasim Akram (Pakistan) - 23 |
| Best Bowling Innings | Ajantha Mendis (6/13) |
| Highest ODI totals at National Stadium, Karachi | ||||||||
| Team | Score | Overs | RR | Inns | Opposition | Ground | Result | Match Date |
| India | 374/4 | 50 | 7.48 | 1 | India | Karachi | won | 25/06/08 |
| West Indies | 360/4 | 50 | 7.2 | 1 | West Indies | Karachi | won | 13/10/87 |
| Pakistan | 355/4 | 49 | 7.24 | 2 | Pakistan | Karachi | won | 12/02/25 |
| Pakistan | 353/6 | 50 | 7.06 | 1 | Pakistan | Karachi | won | 15/12/05 |
| South Africa | 352/5 | 50 | 7.04 | 1 | South Africa | Karachi | lost | 12/02/25 |
| India | 349/7 | 50 | 6.98 | 1 | India | Karachi | won | 13/03/04 |
| Pakistan | 347/5 | 50 | 6.94 | 1 | Pakistan | Karachi | won | 21/01/08 |
| Pakistan | 344/8 | 50 | 6.88 | 2 | Pakistan | Karachi | lost | 13/03/04 |
| Pakistan | 334/6 | 50 | 6.68 | 1 | Pakistan | Karachi | won | 05/05/23 |
| Sri Lanka | 332/8 | 50 | 6.64 | 1 | Sri Lanka | Karachi | won | 30/06/08 |
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