Why doctors are keen on Plasma: ICMR chief said last week that plasma therapy could be removed from the list of Clinical Management Protocols for Covid-19. Despite this, its demand continues full steam. Currently, plasma therapy is an investigational therapy permitted “off label”, meaning for unapproved use outside trial settings. Doctors say the therapy produces genuine results, in contradiction to the findings of a ICMR study. The study itself has been criticised over procedural shortcomings. Experts also point out that the study was conducted on patients in the ‘moderate stage’ of the disease. But the fact remains that the rise