First-time finalist, USA's Jessica Pegula knocked out world number 1 Iga Swiatek on her way to the final. However, Belarus's back-to-back US Open finalist Aryna Sabalenka stands in her way.
The No. 6-seeded Pegula, a 30-year-old from New York, has won 15 of her past 16 matches and will meet No. 2 Aryna Sabalenka for the title on Saturday.
Jessica Pegula will now face unseeded Karolina Muchova of the Czech Republic on Thursday for a berth in the final.
Not since the 2003 U.S. Open have there been two American women and two American men in the semifinals at the same major.
The 30-year-old American hid it well, pulling off a big upset by easily beating Swiatek 6-2, 6-4 at Flushing Meadows and earning a debut trip to the semifinals at a major
Sinner, who took over as the title favorite after Week 1 exits by Novak Djokovic and Carlos Alcaraz, is the only man remaining in the field with a Grand Slam trophy
The eighth seeded Indian-Indonesian pair registered a 7-6(4) 2-6 10-7 win over fourth seeds Ebden and Krejcikova
Swiatek was tied at 4-all with No 16 Liudmila Samsonova on Monday night before grabbing seven straight games en route to winning 6-4 6-1
Two weeks removed from being cleared in a doping case stemming from two positive tests in March, Sinner moved into a showdown against 2021 champion Daniil Medvedev
Three-time defending US Open men's doubles champions Rajeev Ram and Joe Salisbury were eliminated in the third round
The No. 20 seed will attempt to match the best Grand Slam result of his career when he faces No. 9 Grigor Dimitrov on Tuesday for a berth in the semifinals
After the review was complete, an additional angle was seen on the broadcast, USTA spokesman Brendan McIntyre said. The chair did not see this footage prior to making the call
Before this year's appearance in New York, Navarro had never been past the first round at Flushing Meadows
The second seeded Bopanna-Ebden pair lost 1-6 5-7 to the 16th seed Argentine combo of Maximo Gonzalez and Andres Molteni in 66 minutes
Nagal reached a career-high ranking of 68 in July but has dropped to 82 in the latest rankings. India's highest-ranked singles player not being part of the Davis Cup tie is a big blow to the team
Seeded eighth, Bopanna and Sutjiadi were pushed to the brink by Australia's John Pears and Katerina Siniakova of the Czech Republic
Second seeds Rohan Bopanna and Matthew Ebden also moved to third round with a 6-2 6-4 win over Spain's Roberto Carballes Baena and Federico Coria from Argentina
On Sunday, Gauff will face No. 13 Emma Navarro, one of her teammates at the Paris Olympics, for a berth in the quarterfinals
Popyrin defeated Djokovic in a four-set marathon on Saturday
Alcaraz won the French Open in June and Wimbledon in July to raise his career total to four major championships, including taking the title at Flushing Meadows in 2022