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Gum infection may be linked to Alzheimer's disease: Study


A new study published in the journal Science Advances found that could be a potential risk factor of

The bacteria, Porphyromonas gingivalis, known as Pg, causes the chronic periodontitis, causing and potential loss of teeth, reported

The same bacteria was further found in 51 out of 53 brain autopsies of patients, according to new research by Dr. and Casey Lynch, founders of the firm

The company, which is focused on developing therapeutics to alter the course of disease, funded the research.

The team also tested blocking the bacteria in mice by injecting small molecules targeting Pg, to inhibit it and found that it could reduce neurodegeneration in the brain, showing a potential new way to tackle

According to Lynch, her team's publication "sheds light on an unexpected of Alzheimer's pathology -- the bacterium commonly associated with "

Lynch further added that it also shows a "promising approach" to address the disease.

Lynch further added that while previous studies have established a link between and Alzheimer's, the new research observes a "highly significant" link between Alzheimer's and the and that the mouse study indicates causation.

Alzheimer's disease is the most common form of dementia, characterised by that increases over time. It is believed to be caused by a buildup of beta amyloid plaques and neurofibrillary tangles called tau in the brain. There is no cure for the disease as of yet.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Fri, January 25 2019. 07:20 IST