You are here: Home » News-IANS » Lifestyle-Fashion
Business Standard

Aspirin can reduce liver cancer risk: Study

IANS  |  New York 

Taking two or more tablets a week can help reduce the risk of developing primary liver cancer, also called (HCC), according to a research.

HCC is usually diagnosed at a late stage, leading to an average survival time of less than a year and is considered the second leading cause of deaths globally.

Researchers from in the US have found that regular use -- taking two or more 325 mg tablets a week for five years or more -- led to a significantly reduced risk of developing HCC.

"Regular use of led to significantly lower risk of developing HCC, compared to infrequent or no aspirin use, and we also found that the risk declined progressively with increasing aspirin dose and duration of use," said Tracey Simon, research scholar from the varsity.

The primary risk factor for HCC is which can be caused by or C infection, or

"The long duration of aspirin use could be necessary because primary liver takes many years to grow. Aspirin may act at the earliest stages of development, or even at precancerous stages, by delaying or preventing or liver fibrosis," Simon said.

"Since regular aspirin use carries the risk of increased bleeding, the next step should be to study its impact in populations with established liver disease, since that group is already at risk for primary liver cancer," she added.

For the study, appearing in the journal JAMA Oncology, the team examined over 30 years of data on more than 1,70,000 participants who were asked whether they took aspirin on a regular basis -- how many standard-dose (325 mg) tablets they took a week and for how long.

Two or more tablets a week led to a 49 per cent reduction in the risk of developing HCC.

In addition, among those taking aspirin for five years or more, the relative risk was reduced by 59 per cent.

Conversely, regular use of acetaminophen or nonsteroidal anti-inflammatory drugs like ibuprofen had no impact on HCC risk, the study said.



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sun, October 07 2018. 15:24 IST