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Heavy pot smokers may need higher dosage for sedation

IANS  |  New York 

People who regularly use may require more than two times the usual level of when undergoing medical procedures, warns a new study.

"Some of the sedative medications have dose-dependent side effects, meaning the higher the dose, the greater likelihood for problems," said from in Colorado, US.

"That becomes particularly dangerous when suppressed respiratory function is a known side effect," Twardowski added.

For the study, the researchers in examined the medical records of 250 patients who received endoscopic procedures after 2012, when the state legalised recreational

Patients who smoked or ingested on a daily or weekly basis required 14 per cent more fentanyl, 20 per cent more midazolam, and 220 per cent more propofol to achieve optimum for routine procedures, including colonoscopy, showed the findings published in The Journal of the

"Cannabis has some metabolic effects we don't understand and patients need to know that their cannabis use might make other medications less effective. We're seeing some problematic trends anecdotally, and there is virtually no formal data to provide a sense of scale or suggest any evidence-based protocols," Twardowski said.

Cannabis use in the increased 43 per cent between 2007 and 2015. An estimated 13.5 per cent of the adult population used cannabis during this period, with the greatest increase recorded among people 26 and older, according to the study.

--IANS

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(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Tue, April 16 2019. 20:04 IST
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