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Method to identify antibiotic-resistant bacteria developed

IANS  |  Moscow 

Researchers have developed a novel method to quickly identify single antibiotic-resistant cells, which are agents of (TB).

The new method -- called the Raman scattering spectrography -- helps find the and evaluate its resistance to without damaging the biological material. It can also help in analysing bacterial cells.

Raman scattering spectrography helps identify the composition and structure of the studied material based on the scattering of with certain wavelength by its sample.

For the study, the team used bacterial strains obtained from lung expectorations of patients, as well as from bone tissue samples taken during

To obtain information about the structure of cells belonging to different strains, the researchers pointed the beam at different during the procedure.

The findings, published in Data in Brief, showed the cells of different strains appeared to scatter the light differently because resistance to occurs due to changes in the composition of bacterial cell wall components. helped identify differences in the cell walls of drug-resistance and drug-sensitive bacteria.

The data contained information of spectrums typical for different strains of Mycobacterium The caused by antibiotic-resistant strains of is very dangerous.

Raman may be a useful tool for determining the level of drug resistance in tuberculosis agents, said Andrey Zyubin, from the in Russia.

The strains of the family (named after the city where they were first observed) have also become resistant to many medicinal drugs. Methods of quick identification of drug-resistant bacteria are required both for clinical practice and scientific research, the study suggested.

Tuberculosis is one of the top 10 causes of death worldwide, according to

--IANS

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(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Wed, February 13 2019. 16:36 IST
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