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Novel bed net provides greater protection against malaria

IANS  |  London 

A new kind of bed net can emerge as a potent weapon against as a two-year trial involving more than 15,000 children has shown that it can significantly increase protection against the

The trial in showed that a long lasting insecticidal net treated with a called piperonyl butoxide (PBO LLIN) reduced the prevalence of by 44 per cent and 33 per cent in the first and second year respectively, compared to a standard net treated with pyrethroid only.

The study, published in the journal Lancet, also showed drastic control through indoor residual spraying (IRS) with the insecticide pirimiphos methyl, which after a single spray round reduced malaria infection by 48 per cent for an entire year.

"The trial is the first clear evidence that nets treated with piperonyl butoxide can significantly improve personal and community protection from malaria compared to standard pyrethroid-only nets in areas where there is high pyrethroid resistance," said from London School of Hygiene and Tropical

"It also demonstrated that pyrethroid resistance is now a significant problem in some areas and standard LLIN are less effective than before, and that the new IRS controlled malaria for an entire year before needing to be re-sprayed," Rowland said.

Anticipating the possible failure of current due to resistance, the (WHO) and the London School of Hygiene and Tropical have been collaborating with the industry for almost 20 years to develop new types of LLIN and new insecticides for IRS.

One of these is a novel LLIN which incorporates piperonyl butoxide (PBO), a which blocks the natural defence mechanisms of insects - the oxidase enzymes that would otherwise metabolise insecticide - which means the pyrethroid on the LLIN remains potent against mosquitoes despite resistance.

This stops insects from breaking down the pyrethroid within their bodies, so the insecticide stays toxic to the insect.

--IANS

gb/mr

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Thu, April 12 2018. 18:04 IST
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