In an official statement, the organisers said the residency, to be held at Park Theatre at the Park MGM Las Vegas resort, will offer two kinds of shows to the fans of the pop diva.
The main feature will be Lady Gaga Enigma, described as a "brand new odyssey of her pop hits".
"I can't wait to share ENIGMA with all of my fans and with Las Vegas. We're creating a show unlike anything I've done before," the six-time Grammy award winner said in the statement posted on her official website.
"It will be a celebration of all that is unique and different within us. The challenges of bravery can be overcome with creativity and courage that is grown out of adversity, love and music," she added.
Gaga also posted the details of the residency, which will include 27 concerts in total -- 23 Enigma performances and four of the Jazz And Piano shows.
The pre-sale tickets will be available from August 13.
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